BIOtecnia Vol. 16, Núm. 1 (2014) > Vargas-Sánchez

MECANISMOS INVOLUCRADOS EN LA ACTIVIDAD ANTIOXIDANTE Y ANTIBACTERIANA DEL PROPÓLEOS

R D Vargas-Sánchez, G R Torrescano-Urrutia, A M Mendoza-Wilson, B Vallejo-Galland, E Acedo-Félix, J J SánchezEscalante, M C Peñalba-Garmendia MC, A Sánchez-Escalante

 

Resumen

El propóleos es un producto elaborado por las abejas, que se caracteriza por poseer propiedades antioxidantes y antimicrobianas, las cuales son atribuidas a la presencia de compuestos polifenólicos, principalmente flavonoides. Estos compuestos son de bajo peso molecular y en su estructura química contienen un número variable de grupos hidroxilos. Varios investigadores han reportado que los mecanismos antioxidantes propuestos para estos grupos son mediante secuestro de radicales libres, o actuando como substrato para radicales, tales como superóxido e hidroxilo, y quelación de iones metálicos. Mientras que el mecanismo antimicrobiano involucra la inhibición de ácidos nucleicos y degradación de la membrana citoplasmática.

Palabras clave

propóleos; mecanismo antioxidante; antibacteriano; flavonoides.

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Referencias

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